ABSTRACT
OBJECTIVE： To analyze the application of antibiotics in 18 community health service centers in Shanghai Chongming district， and to further strengthen rational use of antibiotics. METHODS： By retrospective analysis， statistical analysis was made on the monitoring data of antibiotic use and 21 600 prescriptions reported by 18 community health service centers in Chongming district of Shanghai from Jan. 2016 to Dec. 2018 in respect of antibiotics use， top 5 antibiotics in the list of DDDs， prescription analysis， etc. RESULTS： From 2016 to 2018， the average annual total income of medical treatment， drugs and antibiotics of 18 community health service centers in Chongming district of Shanghai were 490 499 000 yuan， 427 231 500 yuan and 41 602 900 yuan respectively. Annual average incomes of outpatient and inpatient antibiotics were 35 435 700 and 6 262 100 yuan. Annual consumption amount of antibiotics were 2 129 627.71 and 70 829.51 DDD. The proportion of antibiotics was 9.76％. Annual antibiotics use density （AUD） was 29.41 DDD. Compound annual growth rate （CAGR） was negative for antibiotics ratio （－3.27％）， outpatient antibiotics consumption amount （－18.40％）， antibiotics consumption amount for outpatient per time （－17.83％）， inpatient antibiotics consumption amourt （－1.25％） and AUD （－0.98％）. The dosage form of top 5 antibiotics in the list of DDDs within 3 years were oral preparation， among which cefuroxime， cefaclor， levofloxacin and cefpropene were all ranked in the top five in three years. In 21 600 prescriptions， average number of drug per prescriptions was 1.99， the average amount of prescription was 120 yuan， and the number of antibiotics types used accounted for 8.24％ of total drug types； 15.43％ of the prescriptions used antibiotics， the average amount of the prescriptions containing antibiotics was 114.46 yuan， and the total amount of antibiotics accounted for 8.24％ of the total amount of the prescriptions. CONCLUSIONS： The rational use of antibiotics in Chongming community health service center has been continuously improved， and can provide reference for drug management of primary hospitals.
ABSTRACT
Objective To evaluate the clinical curative effect of ammonia bromine,oral solution (Yitanjing) auxiliary for the treatment of children with bronchopneumonia.Methods The clinical data of 64 children with acute bronchopneumonia with breathing were retrospectively analyzed.According to different treatment,they were divided into three groups,three groups were intravenously given anti-infective drug therapy,group A (22 cases) treated with Yitanjing,B group (21 cases) treated with ammonia bromine rope,group C (21 cases) treated with hydrochloric acid C quattro.Before and after the treatment,cough,sputum improve scores,and the changes of pulmonary function,hospitalization time were observed.The clinical efficacy of three groups of children with and medication compliance were evaluated.Results In group A,group B and group C,the effective rates were 95.45％,90.48％ and 95.45％ respectively,the effective rate of group A was significantly higher than group B and group C (x2 =3.88,4.27,all P ＜ 0.05) ;In group A good taste, convenient selected rates were 95.45％,95.45％,which were significantly higher than 85.71％,90.48％ of group B (x2 =4.17,3.86,all P ＜ 0.05) and C group (47.62％,71.73％) (x2 =8.67,6.86,all P ＜ 0.05).Conclusion Ammonia bromine,oral liquid can effectively improve pulmonary function in children with acute bronchial pneumonia and clinical symptoms such as cough,sputum,high compliance.